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Why does kidney failure cause anemia?

2017-05-27 11:22

Life, suffering from kidney failure increasingly large groups, for patients with chronic renal failure, clinical anemia is a normal phenomenon, then what is the reason of it, through the following article let us understand simple.

Chronic renal failure is the most common disease in the clinic. When most people suffer from chronic renal failure, anemia occurs. Generally speaking, it mainly includes the following aspects:

First of all, the most common form of anemia is the loss of erythropoietin, and experts say erythropoietin is produced mainly by glomeruli, near cells, and mesenchymal cells. Chronic renal failure, in addition to the kidney to produce erythropoietin damaged parts, reduce the affinity of hemoglobin for oxygen, the hemoglobin for oxygen increased rate of renal ischemia is not serious, the main factors to reduce erythropoiesis, resulting in significantly reduced erythropoietin. There are toxins to suppress bone marrow, chronic renal failure, blood accumulation of certain toxic substances on the bone marrow has a direct inhibitory effect, leading to hematopoietic dysfunction.

In addition, if the chronic renal failure patients with increased destruction of red blood cells is one of the causes of anemia, this is because the effect of high polyamine levels cause shortening of life span of red blood cell autolysis, uremic erythrocyte metabolism and erythrocyte fragility increased, erythrocyte induced by autolysis, microvascular disease causes red blood cells to mechanical damage destroy and hypersplenism.

As well as increased red cell loss, chronic chronic upper gastrointestinal or lower digestive tract occult bleeding, laboratory frequent blood test or residual blood loss in dialyzer can aggravate the situation of patients with chronic renal failure. Other diseases may lead to, such as hypertension, diabetes and so on, some diseases may affect hematopoietic function, but also may affect the body's absorption of nutrients, resulting in malnutrition and induce this phenomenon.

Editor's note: to understand the causes of anemia phenomenon in patients with chronic renal failure, remember that in the treatment of chronic renal failure disease, must be symptomatic treatment, so as to quickly restore health. I wish you good health.

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