What are the side effects of urea nitrogen?2017-01-24 17:59
There are a lot of friends that high urea nitrogen on the body can not be a very big damage, over time is good. So, urea nitrogen really no side effects? Let's take a look at my site under the kidney hospital hospital nephropathy experts for everyone to explain, what is the side effect of urea nitrogen?
What are the side effects of urea nitrogen? How to control the high level of urea nitrogen on the site is often the patient raised such questions. In fact, nephropathy serum creatinine, high blood urea nitrogen in microcirculation damage, glomerular sclerosis and basement membrane injury as the main pathogenesis principle change. To solve the problem of high urea nitrogen, it is necessary to start from the causes of this disease, the treatment can be completely.
For patients with kidney disease, occult blood nitrogen high in two cases. The most common is renal insufficiency, including acute renal failure and chronic renal insufficiency, mainly impaired renal function, blood urea nitrogen can not be discharged from the urine; second a few acute lupus nephritis, nephritic patients may also exhibit a transient rise in the blood urea nitrogen mainly in height, edema, oliguria for urea nitrogen in the blood can not be made with the urine volume in the blood caused by.
In the past, the treatment of high urea nitrogen can not fundamentally control the patient's condition, and it is affected by a variety of reasons, and sometimes show false impression of patients. The development characteristics of traditional Chinese medicine treatment methods is to block renal fibrosis, fundamentally repair damaged renal function expansion, renal artery, renal damage increase effective blood perfusion, increase the oxygen supply to the kidney, improve renal microcirculation, reduce glomerular pressure, accelerate the repair of damaged cells, glomerular lesion structure, functional recovery. To increase the amount of urine, blood inosine, urea nitrogen excreted from the body in control patients with poisoning.
Urea nitrogen is the main end product of protein metabolism in human body. Deamination of amino acids produced NH3, and C02, two of patients in the liver synthesis of urea, each G protein metabolism to produce urea 0.3g. Urea nitrogen content of 28/60, almost half. Usually the kidney as the main organ excretion of urea, urea from glomerular filtration in each tubule can be absorbed, but the renal tubules urine flow more quickly absorbed less, which reached the maximum rate of clearance. And the blood inosine, in early renal damage, blood urea nitrogen in normal range. When the glomerular filtration rate decreased to below 50% of normal, the concentration of nitrogen was increased rapidly in occult blood. Under normal circumstances, occult blood nitrogen with inosine ratio (BUN/Scr) value is about 10, high protein diet, high catabolic state, water shortage, renal ischemia, blood volume without feet and some acute lupus nephritis, can make the ratio increased, even up to 20 ~ 30; and low protein diet, liver disease often lower the ratio, this can be called low nitremia.
Normal adult fasting BUN was 3.2-7.1mmol/L (9-20mg/d1). A variety of renal parenchymal disease, such as lupus nephritis, interstitial lupus nephritis, acute and chronic renal damage, kidney spaceoccupying lesions and imbalance can make blood nitrogen. Many reasons can cause kidney occult blood nitrogen increased, such as the exclusion of kidney outside reason, BUN), 21.4mmol/L (60mg/d1) is one of the high diagnostic index of uremic serum creatinine.
Therefore, urea nitrogen must be effective to control, if the urea nitrogen for a long time can not be controlled, the side effects of the kidney is great.