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Congenital nephrotic syndrome

2017-06-25 11:47
Nephrotic syndrome as a common pathological type of kidney disease, with its typical "three high and one low" clinical symptoms are characterized. In clinical, nephrotic syndrome is divided into congenital nephrotic syndrome and acquired nephrotic syndrome, congenital nephrotic syndrome and acquired nephrotic syndrome can be divided into primary nephrotic syndrome and secondary nephrotic syndrome two Type. Congenital nephrotic syndrome, the number of patients with fewer, the majority of patients with nephrotic syndrome or later to the main nature of the main. What is congenital nephrotic syndrome?
Congenital nephrotic syndrome is a relatively rare infant kidney disease, once suffering from congenital nephrotic syndrome, the consequences of kidney disease in children with serious consequences. The same time as the above-
Congenital nephrotic syndrome refers to the onset of about 3 to 6 months after the onset of a kidney disease, it has four major characteristics of nephrotic syndrome, namely, hypoproteinemia, serum albumin <3g / L; high cholesterol Hyperlipidemia, serum cholesterol more than 5.72mmol / L; edema. Congenital nephrotic syndrome is divided into primary and secondary, the primary is the first type of congenital nephrotic syndrome in Finland, secondary to secondary infection (such as congenital syphilis, giant cell inclusion body virus, rubella, hepatitis) , Poisoning, hemolytic uremic syndrome. 
Finnish congenital nephrotic syndrome is an autosomal recessive inheritance, children often premature children, a large placenta, nose, low nose, eye width, muscle tension is poor. Born with proteinuria, edema and ascites soon, and often umbilical hernia, children feeding difficulties, easy to vomit and diarrhea, growth and development retardation, some children may be hypercoagulable state, leading to thrombosis complications. Congenital nephrotic syndrome in children with early normal renal function, but susceptible to infectious diseases. The disease without specific treatment, only symptomatic and supportive therapy, prevention and treatment of infection, reduce edema, steroids and immunosuppressive agents invalid. The disease is poor prognosis, more than 6 months to 1 year old died of infection, such as survived to 2 to 3 years old often died of uremia. So the most thorough treatment is 2 years of age after renal transplantation.
Reminder: nephrotic syndrome longer course, easily recurrent. To maintain a year and a half to two years of standardized treatment. According to clinical data, some children two or three years old when the disease, to 10 to 12 years old when the disease is still not good, upper respiratory tract infection is repeated scourge. Long-term recurrent can affect the growth and development of children, so that nephrotic syndrome has become extremely difficult to cure. 
After the occurrence of nephrotic syndrome, care to prevent colds, children should not eat more salt food and high protein. The child's activity should be strictly limited. Children should not wear clothes for a long time. Should not be reduced or withdrawal. In addition, usually should pay attention to observe the child's urine, such as the child's urine color changes have been found, should be promptly sent to the hospital urine test. Pediatric nephrotic syndrome should choose a regular hospital, standard medical treatment, to avoid repeated illness and exacerbate the disease, damage to renal function, for the further rehabilitation of the latter to increase the difficulty.

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